GLONOINUM Valuable in Cerebral Congestions and Sciatica

Glyceric trisnitrate, C3H5 (NO3)3. Nitro-glycerine; product of action upon glycerine of a mixture of nitric and sulphuric acids.
Its taste is sweet, pungent, and aromatic; but in ascertaining this great precaution should be used, for a very minute quantity put upon the tongue produces a violent headache for several hours. This effect was experienced by several persons in my laboratory, and I have frequently felt it myself.
(SORRERO, Comptes Rendus, Feb. 15th, 1847.)
Dr. HERING, struck by the foregoing observation, tested Gl. (so named by him from its then chemical formula) on a number of healthy persons, and published his results in the Brit. Fourn. of Hom., vol. vii (1849), and again more fully in his Amerikanische Arzneipriifungen, Nos. 1 and 2 (1853). From
the letter work we select the following :
MORRIS DAVIS took 1/10 dr. observed a kind of burning on sundry small spots on lips. After 10 m. throbbing in temples and rush of blood to head, temporal arteries throbbed perceptibly; pain over eyebrows; the slightest shaking of head increased headache, this lasted 30 m. On walking in street, all the
objects seemed starting, the houses did not seem in their right places; the way home seemed 3 times longer than usual. (Am. Arzneipr., 46.)
GENERAL ANALYSIS
Acts upon the medulla oblongata and the pneumogastric and paralyzing the peripheral vaso-motor nerves, producing active (Amyl nitrite, passive) cerebral hyperaemia and palpitation of the heart, the former presenting symptoms closely resembling those resulting from exposure to the sun's rays, even to the intense degree of sunstroke, yet lacking the important symptoms of fever and inflammation which characterize cerebral disorders caused by Aconite and Belladonna. Its action is not so evanescent as that of Amyl
nitrite. The chief characteristic of Glonoine is a pulsating, throbbing fullness (not pains) in the brain.
THERAPEUTICS
Glonoine is a valuable remedy in cerebral congestions, especially when resulting from exposure to the rays of the sun, or from mental excitement, fright or fear. In such cases the face is pale; and, while there is a severe bursting or crushing pain, the chief characteristic is a throbbing or pulsation all through the head with every beat of the pulse, but which is not painful, and a sort of undulating or wave-like motion in the brain. Sometimes the attacks come on suddenly, the patient becomes dizzy and loses his way, perhaps falls down unconscious. These symptoms may be hemicrania, or threaten an attack of apoplexia, or, occurring from exposure to the sun's rays, if continued, result in sunstroke, in which Glonoine is a most efficient remedy if the symptoms correspond as they frequently do. (Compare Bell., Natr. c.).
Cerebro-spinal meningitis. Cerebral congestions from suppressed menses. Hydrocephalus.
The mental symptoms of Glonoine may result from mental shock, or from mechanical injuries , or their later consequences, or from exposure to the sun's rays. but they are usually associated with more or less of the cerebral symptoms mentioned. Also pains and other sensations long after injuries. Familiar things seeming strange, and the patient lose his way are very characteristic. Acute mania. Insanity. Useful in supra-orbital neuralgia, also in neuralgia of the face, extending through the head, with painless throbbing. According to Farrington, Glonoine is useful in retinal congestions, even apoplexia from exposure to a bright light. Sometimes in sea-sickness with characteristic cerebral symptoms. Glonoine is frequently a
remedy for epileptiform convulsions, falling down unconscious with frothing at the mouth; puerperpal convulsions. Allen recommends Glonoine in Angina pectoris, where there is fluttering of the heart and violent beating, as if it would burst the chest open, with labored breathing, pains radiating in all
directions, even into the arms, with loss of power in the arm.
CONSTITUTION
Suited to: Florid, plethoric, sensitive women, nervous, sanguine, readily affected persons.
CAUSATION
Ill effects of sun-heat, bright snow, fire-heat, fear or fright, jarring injuries.
MODALITIES
Better from open air, elevating head. cold things, cold application.
Worse in sun, exposure to sun-rays, open fire, stooping, stimulants, lying down from 6 a.m. to noon,
left side. heat on head, sun,overheated, hot weather. motion. jarring, shaking, bending head back injury, suppressed menses, fruits, weight of a hat, wine, gas-light, cutting hair, peaches.
MIND
Falling down, with loss of consciousness nd alternate palpitation of the heart and congestion of the head. Confusion of ideas (Bapt., Gels., Phos.ac); cannot tell where he was; well-known streets seems strange; the way home too long; forgets on which side of the street he lives.
HEAD
Vertigo; worse from stooping or moving the head (Bry.); worse in the open air; with nausea; with dim vision. Inclination to bend the head backwards, or to hole it with the hands. Sensation as if the head were
enormously large (Arg. nit., Bovis., Cimic., Zing.). Fullness in the head; distinct feeling of the pulse in the head (Bell.); throbbing without pain.
Sensation as if the blood were mounting to the head (Bell.); as if hanging head downward. Tensive pain over the eyes and nose, also behind the ears followed by choking sensation about the throat. Skull seems too small, as if the brain were attempting to burst the skull (Cimic.); violent action of the heart, and a distinct pulsation over the whole body. Sensation of soreness through the whole head; is afraid to shake the head, as it seems that it would make the head drop to pieces. Throbbing in the head; in forehead; in temples; in vertex; in occiput; worse when moving (Bry.); better when sitting still and lying and from pressure (Bell). Cracking sensation in the brain. Shocks in the brain synchronous with the pulse. Undulating or wove-like in the brain (Cinch.). Throbbing in the temporal arteries, which were raised and
felt like cords (Bell.). Severe pain in the occiput; extending to the eyes and temples. Congestion in occiput, seems as if he would lose his reason. Headache deep in the brain; rising from below upward; extending to nose.Headache and pulse increase and diminish together. Headache with nausea; with dull heavy pain in stomach. Headache aggravated mornings and forenoons. Shaking the head increases the headache; also motion (Bry). Headache worse from the heat of the sun (Bell., Natr. carb.); better in the open air and
from pressure. Headache, throbbing, etc., during or in place of menses (Cinch.)
EYES
Sparks and flashes before the eyes (Bell., Cycl.); black spots on attempting to stoop. Objects dance with every pulsation. Pressing, protruding pains in eyes. Eyes injected, protruding, look wild (Bell., Hyos.). Pupils dilated, eyes rolled upward (Bell.).
EARS
Deafness, ears feel as if stopped up (Coni.). Ringing in the ears, audible pulse.
FACE
Pale during heat, sunstroke, congestion, etc.; flushed and hot with headache. Redness of the face, which comes and goes. Gnawing pain in the masseter muscles.
STOMACH
Increased desire to smoke. Nausea and vomiting in congestion or during sunstroke. Eructations. Nausea. Faint feeling at pit stomach, also with throbbing.
FEMALE
Instead of menses congestion to head; face pale; worse in warm room; fainting; throbbing. At climaxis, flushes of heat, pressure in head, nausea, loss of senses, vertigo, swelling of feet. Eclampsia; unconscious;
face bright-red; puffed; pulse full, hard; urine copious and albuminous.
HEART
Violent action of the heart, distinct pulsation over the whole body. Excessive perceptible palpitation of the heart (Spig.). Pulse accelerated; rise and falls alternately; low and feeble in sunstroke. Pulse rapid when walking; during headache; full pulse. Laborious actions of the heart oppression. Sharp pains in heart; on stooping; extending to between the shoulders. Purring noise in region of heart when lying , pulse intermittent.
RESPIRATION
Inclination to deep respiration. Constriction and oppression of the chest.

GENERALITIES.
Great weakness and prostration (Ars., Bry., Cinch., Phos.).
Painless throbbing in the whole body (Ant. crud., Puls., Sil., Sep., Zinc.).
Seeming plethora, rapid deviations in distributions of blood. Falling down unconscious, with convulsions and frothing at mouth, after alternations of palpitation and congestion to head.
RELATIONS
Antidoted by; Acon., Camph., Coff., Nux v.
Compare; Amyl nit.; Act.r. (Waving in brain); Petrol and Crotal.h. (Loss of location); Bell, (cephalic cry but not as marked in Bell. Has > bending head back, and > covering head; Glon. > uncovered); Apis, Hyo. (Fears being poisoned); Gels. (Inclination to jump out of window); Stram.; Sang. (Headache with the sun; ear sensitive to jar); Nit.ac. And Bell. ( sensitiveness to jar); Melilot. (Headache with crimson face); Lyc. And Phos. (Burning between shoulders); Dig. And Diosc. (Headache extending into nose); Sec. (Fingers
spread apart)

GNAPHALIUM
Gnaphalium polycephalum.
Sweet-scented Everlasting Flower. N.O. Compositae.
Tincture of fresh plant.
The name Gnaphalium comes from Gr. gnaphalion, woolly, in allusion to the very woolly foliage; polycephalum means 'many heads,' referring to the numerous flower heads. The plant is indigenous to the eastern states of North America, growing in old fields and on dry, barren lands.
The leaves have a pleasant aromatic smell and an aromatic, slightly bitter, astringent, agreeable taste. The dried flowers are used as a sedative filling for the pillows of consumptives.
Proved by Banks, Fuller and Woodbury.
Gnaphalium is mainly used in the disorders of the sciatic nerve, though it has some useful abdominal and female symptoms. A remedy of unquestioned benefit in sciatica, when pain is associated with numbness. Rheumatism and morning diarrhea. Polyuria.
Intense sciatic pain, alternating with or followed by numbness, worse lying down, motion, stepping, better by flexing the limbs on abdomen, by siting in a chair. Lumbago with numbness of part and weight and heaviness in pelvis. Anterior crural neuralgia. Pain in joints as if they lacked oil.
Offensive diarrhea with colic, worse morning. Weight and heaviness in pelvis. Dysmenorrhea with scanty menses and very painful the first day.
REGIONS
NERVES [SCIATIC; crural; abdominal]. Prostate gland. Mucous membranes [bowels].
MODALITIES
Better from flexing limbs, sitting in a chair. Worse from walking, lying, cold damp.
CLINICAL CONDITIONS
Anterior crural neuralgia. Cholera. Cholera infantum. Colic. Diarrhea. Dysmenorrhea. Gout. Lumbago. Night-sweats. Prostate gland. Rheumatism. Sciatica.
EXTREMITIES
Feeling of weakness, as if incapable of raising the slightest weight. Rheumatic pains in elbows and shoulders. Cramps in calves of legs and feet when in bed. Rheumatic pain in ankle joints and legs. Intense pain along the sciatic nerve, numbness alternates with pain. Frequent pains in calves and feet. Gouty pains in big toes. Better drawing limbs up, flexing thigh on abdomen. Gouty concretions. Anterior crural neuralgia. (Staph.) Pain in joints as if they lacked oil. Chronic muscular rheumatism of back and neck.
GIT
First stage of cholera infantum, vomiting and purging. Rumbling in bowels with stool before breakfast. Looseness of bowels with passage of pale-colored feces. Diarrhea discharge in morning and during day with irritable temper, pains in bowels in children. Dark-colored, liquid offensive stool in morning
afterwards pain in bowels all day.
Gnaphalium: Pain commences in hip and rushes downward posteriorly to foot; leg feels cramped and must be drawn up.
Colocynthis: Pain extending from hip, down posterior portion of hip into popliteal region; pains sharp and shooting; patient must keep perfectly quiet as every motion <.
Ammonium muriaticum: Pain severe and long continued; often left-sided; tendons of left side feel as if too short, making the patient lean sideways >while walking; pain < sitting; > walking, lying down.
Calcarea carbonica: Sciatic pain caused by working in water; pain < letting leg hang down; has to elevate knee constantly.
Euphorbium: Tearing and tingling pain > motion.
Kali phosphoricum: Almost a specific for neuralgia when the patient feels most of the pain in the sole of the foot; he is very restless.
Indigo: Violent pain from middle of right thigh to knee & stiffness of leg; < rest, sitting; > walking.
Palladium: Right side; darting pain from toes to hip, or downward from trochanter into popliteal region; patient cannot remain lying, must constantly stand up.
Stillingia: Left side; violent [bone] pains from hip to middle of thigh and to toes.
Tellurium: Right side; pain from sacral region to thigh & sensitiveness of spine; < least exertion, laughing, coughing, lying on painful side.
Viscum album: Serious cases; tearing, throbbing pains in both thighs; sensation as if muscles were twisted with hot pincers; leg feels heavy like lead; < touch, least motion; > rest
Rhododendron: Pain as if sprained in hip and knee joints; sensation of coldness in skin over affected region; < rest, stormy weather.
RELATIONS
(1) Xanth., Cham., Coloc., Ip., Merc., Puls., Lyc., Caul.

List of references;
1. Allen .H. C.—Key Notes on Materia Medica..
2. Boger. C.M - A Synoptic to the Materia Medica
3. Boricke . W- A Pocket manual of Homoeopathic Materia Medica
4. Burnett . C –Best of Burnett, compiled by Dr.H.L.Chitkara.
5. Clarke. J.H – Dictionary of Practical Materia Medica.
6. Cowperthwhite -- Materia Medica
7. Farrington . E. A. – Clinical Materia Medica.
8. Hering .C – The Guiding symptoms of our MM.
9. Kent. J. T. Lectures on Materia Medica.
10. Murphy .R - Lotus Materia Medica.
11. Nash. E.B - Expanded work, Compiled by Dr. P. Sivaraman

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