GLONOINE-NITRO-GLYCERINE [Glon]:
-M.L.Tyler.
Introduction:
GLONOINE-Nitro-glycerine-that highly explosive liquid , which, admixed with some pours earth forms the "deadly dynamite to the shaking of earth and the blasting of rocks ,lives up to its reputation, even when potentized and used in medicine; retaining its alarming characters: its suddenness, its bursting sensations and pains,its upward-surging which threaten to lift and shatter the cranium. Chemistry is fascinating, of only for its psychology, if one may (mis) use the term. Of two deadly elements, in combination,she may form something quite harmless,m even essential to life: whereas from such mild and kindly creatures as the glycerine of the toilet table so inert that it never even "goes bad", and nitrogen, that colourless, tasteless, odourless gas, which, four- parts to one in mixture with the life-supporter, oxygen, modifies the properties of the latter in such sort that, instead of burning us out rapidly, we just get, with every breath, that happy admixture that supports life without hastening its destruction. That nitrogen and glycerine should combine to produce such a wildly intemperate blasting agent is incalculable- absolutely unforeseen till "discovered". But, as a great chemist once said, "no one could tell, a priori, how even a lump of sugar would behave when dropped into a cup of tea". Science is the plodding daughter of Experiment: and, as such, Homoeopathy is scientific. Dr. HUGHES (Pharmacodynamics) points out that, though Old School uses Glonoine, having even adopted that name for it, yet medicine owes its introduction to Constantine Hearing, Hahnemann's great disciple. But we notice that, as always, when using those violent medicinal substances, so often the most splendidly curative agents of Homoeopathy, Old School has, perforce, to follow into the fantastic region of infinitesimals. "Nitro-glycerin was discovered by Sobrero in 1847, but none could be obtained for physiological experiment until Morris Davis, a Philadelphia chemist, in the same year, after long and laborious trials, under direction of Hering, succeeded to produce the substance in sufficient quantity for proving. It was extensively proven here and abroad (see Allen's "Encyclopedia") and the symptoms have received abundant clinical verification."-- HERING'S "Guiding Symptoms" A quaint little verification of the care and exactness with which the provings of homoeopathic drugs have been observed and recorded comes to hand, most opportunity, even as we write. A certain physician,busy with rather urgent mental work,and worried by a sensation of fullness at the back of head and neck, -a miserable, incapacitating fullness-took a dose of Glonoine--a drug that, as we know, produces such fullness,and there. It was Glonoine 3, merely a couple of pilules, of the only preparation available, probably inert, discovered among a number of homoeopathic medicines that had belonged to some on long since dead-(certainly 25 to 30 years) Well, the headache soon went (post or proper hoc?)-but a couple of days later,while busy with out-patient work, the doctor became suddenly conscious of an unpleasant numbness of the left had, never felt before,and rather disconcerting. Presently this disappeared,but only to be succeeded by numbness of the lower lip, -the exact sensation felt when cocaine has been injected for tooth extraction,. this also went: but only to return again and again and yet again first to left hand and then to lower lip: nowhere else: always absolutely limited. Before night these rather alarming sensations sent him to Kent's Repertory to find the remedy-should it be needed. And there he discovered,under "numbness, lower lip{, drugs only "(Calc),and Glon." Then he turned to "Numbness of left hand", to find several remedies: Glon. among them! The sensation was satisfactorily accounted for: and was the more interesting because Glon. is not down as producing numbness of right hand, or of upper lip.
BLACK LETTER SYMPTOMS
Well-known streets seem strange: way home too long. Disinclined to speak; would hardly answer. A distinct feeling of pulse in HEAD Throbbing in front of head. Immediately a sensation as if head were too large. Head felt enormously large. Pressure and throbbing in temples. Pressure and pain from within out in both temples. Fullness in head,and throbbing without pain. Head very full: pulse full;l and quick. As if the blood were mounting to head. As if he were hanging with head downwards,and as if there were a great rush of blood into head in consequence. As if skull were too small; and brain attempting to burst it. Afraid to shake his head lest it drop top pieces. Holds head with both hands; presses sinciput. Shocks in brain, synchronous with every pulsation of arteries. Undulating sensation in head. Throbbing in head: in temples: in temporal arteries which were raised and felt like whipcords. Sensation of fullness, vertex and forehead. Shaking the head increases the headache. Headache on damp,rainy days; after taking cold; after much sitting, and mental exertion. Red injected hot EYES during headache, with wild expression. Throbbing pain in all the TEETH. Throbbing in while BODY. Intense congestion of brain induced in plethoric constitutions by sudden SUPPRESSION OF MENSES, or appearing instead of menses. Headaches occurring after profuse uterine haemorrhage. Rush of blood to head in pregnant women, with pale fact and loss of consciousness. Violent palpitation of HEART, with throbbing carotids,pulsating headache in forehead and between temples. Blood seems to rush to heart and mount rapidly into head. Epileptic CONVULSIONS,with congestion to head and heart. Bad effects from being exposed immediately to SUN'S rays. (In fever) flushes of heat: weaves of heat upwards.
ITALIC, OR QUEER SYMPTOMS
Recognized no one. Raved; screamed wishes to rush from house. Jumped out of bed,but legs gave way. Fears: throat swollen;chest as if screwed together; of approaching death; of having been poisoned. Bad effects of fear,fright,mechanical contusions and their late consequences. Could not allow head to be level with body. Confusion of ideas: could not tell where he was. Loss of location: (a cured case) began ten years ago; loses himself in streets he was travelled in for years. All right in regard to everything else. In familiar street everything strange. Had to look about him every few minutes to convince himself he was in. he right street. Houses not in their right places, on the route he had traversed at least four times a day for four years. Convulsions,falls down from thing at mouth, after alternations of palpitation of heart and congestions to the head. Congestion to head,causes sensation of coldness every time. Tight and khaki feeling throat,k like strangulation. Skull too small. as if brain attempting to burst skull. As if head and neck laced ion: clothing too tight. Pain in wens on scalp. as of a thimble pressed firmly on them. Every motion,side to side,. increased the pain (in head), but motions backward and forward did not. Headache: ceases in sleep: better in open air:;lessened by drinking coffee, after a raw hours: tea lessens it better. Feels as if ice-cold sweat were on forehead,.which is not there. Rays of sun on head were not to be borne, and head would not allow hat to touch it. Frightful headache: runs about room with head pressed between hands. As if head would burst: knocks it against wall. Hyperaemia of brain caused by excessive cold or heat. Bad consequences of cutting hair. SUNSTROKE. Said her eyes were falling out: felt as if someone were pulling them from within outwards. Letters seem smaller: flashes of lightning,sparks, mist or black spots,whirling and confused vision. Wild, staring look : protrusion of eyes. Supra-orbital neuralgia,from 6 a.m. to 11 or 12. Cold sweat on face during congestion to head. Lower lip feels swollen. Numbness lower lip. Chin feel elongated to knee's: obliged to put hand to chin repeatedly to be sure this was not the case. (Prover had injured chin by a fall twenty years before.) Tongue numb as if burnt; prickling, stinging.' Constriction in throat as if throttled. Wine aggravates all symptoms: alcoholic stimulants cause delirium, congestion,stupor. Seasickness. Faint, warm sickening sensation in chest and stomach, like threatening seasickness Giddiness. Disturbances in intercranial circulation at menopause. Flushes, etc., during climacteric. Violent palpitation: feeling she would die: Numbness whole of the left arm. Pressure at heart as if it were being contracted. Alternate congestion to heart and to head. "As an intercurrent in angina pectoris, to prevent organism from, getting accustomed to unlicensed of Aur. mur." Hot sensation down back; burning between scapulae. Old contusions and jars (to head and spine). Knees give way in headache. Unsteady gait. Knees and thighs knock together during headache. Convulsions, with clenching and jerking upwards of fists and legs. During spasms spreads fingers and toes apart. Convulsions,with especially left fingers spread apart. Cannot protrude tongue in a strains line. Restless sleeps: wakes with fear of apoplexy. Congestions; blood tends upwards: vessels pulsate; veins, jugular temporal, enlarged. Rapid deviations in distribution of blood. Useful as a substitute for bleeding. Bad effects from mental excitement, fright fear, mechanical contusions and their later consequences,from having hair cut,and from exposure to rays of sun. Antidoted by ACON., Camph., Coffea, Nux. Compare AMYL NITR., Bell., Ferr., Gels., Natrum Carb., Potassium. nitr., Sod. nitr., Stram. As seem from above, the action of Glonoine so local., so sudden,so definite,so alarming and torturing,and therefore so remedial is, once grasped,impossible to forget. In fact, it seems hardly worth writing about ! However we will run through what some of or great prescribers and writers have to say about it. This one emphasizes one point coinciding with his experience,that one another; and so one learns. HUGHES writes: "The name Glonoine was formed by its introducer into medical practice,,Dr. C.Hering, out of the chemical formula (GlO NO5) denoting its composition. Dr. Hering proved it on himself and others in 1948. Hughes says, "The action of Glonoine lies a within a very small compass. If any one will touch his tongue with a 5 per cent. solution,he will pretty certainly find in a few minutes that his pulse has increased by twenty,forty or even sixty beaten. He may feel throbbing all over his body, but will almost always experience it in his head which will go on beating until a pretty violent bursting headache has developed itself. With this, there will be probably some giddiness, a sense of fullness on the head and at the heart,.and ones of constriction about the throat. All this reminds used of Amyl nitrite but the effects of the two drugs are not identical. Amyl causes a general flushing without marked sense of throbbing nor is the pulse much affected by it. It seems to have been demonstrated that Amyl produces its dilating effects on the arteries by directly paralysing their muscular coats while Glonoine affects the nervous centres of the circulation,and is limited to this sphere." Then he distinguishes between the action of Glon. and Belladonna. "With Bell., the circulation within the cranium is excited because the brain is irritated: with Glon., the brain is irritated because the circulation is excited. It would be indicated in such hyperaemia as can be produced by excessive heat or cold, by strong emotions,by mechanical jarring,by suppression of the menses or other haemorrhage and excretions." He evidences not only sunstroke, but the striking benefit he has obtained from the drug in the distressing after-effects of sunstroke. He says, "perhaps the greatest boon which Dr. Hering has conferred upon patients in introducing Glon, to medicine is the relief it gives to menstrual disturbances of the cerebral circulation as the intense congestion of brain induced in plethoric constitutions by sudden suppression of the menses. Glonoine is an exquisite similimum here: for in one of Dr. Dudgeon's provers,who took it while an catamenia were present, these immediately ceased,and the headache went on increasing in violence till night. It does not, like Lachesis or Amyl nitrite, act on the flushings of the climacteric; but is most valuable when these are localized in the head. He says, "it was the statement of its discover, Soberer, that even a very small quantity placed on the tongue causes a violent headache of several hours' duration', which led Dr., Hering to investigate its action." The kind of headache--fullness, tension, throbbing, bursting-- these are the phrases used by the provers to describe it. It acts as rapidly in disease as in health. He discusses its stroking power to relieving paroxysms of neuralgia, even in some cases, permanently curing. GUERNSEY epitomizes Glonoine,.and its uses. "Troubles from heat of the head in type-setters in men who work under a gas-light steadily, so that heat falls on the head: bad results from sunstroke; can't bear any heat about the head; can't walk in the sun, must walk in the shade or carry an umbrella; can't bear heat from a stove; great vertigo from assuming an upright posture from rising up in bed, rising from a seat. Heat in head;throbbing headache." Patient feels lost, or strange even in unfamiliar street or surroundings. Things look strange and unfamiliar. NASH. One of our great head ,medicines. He says he used to carry Glon I in his case, for those inclined to sneer at the young doctor and his sweet medicine. He seldom failed to convince, in five to ten minutes, that there was power here; for a drop on the tongue produced the characteristic throbbing headache. No one ever asked for more proof of the power of Homoeopathic medicine. (One members a young woman doctor at the"New":, as the Elizabeth Garret Anderson Hospital was then called, who described the terrible headache from touching her tongue with some preparation of nitro-glycerine). The pains of Belladonna are sudden in onset, and suddenly gone: those of Glonoine are even more so. Nash says that "Glonoine is better adapted to the first, congestive stage of inflammatory diseases of the brain: Belladonna goes farther, and may still be the remedy after the inflammatory stage is fully initiated." Neither can stand the least jar. But pain "waves" upsurging, are absolutely characteristic of Glon. FARRINGTON emphasizes that the keynote to the whole symptomatology of the drug is expressed in this one sentence: "a tendency to sudden and violent irregularity of the circulation." With that, he says,we can easily work out the other symptoms. "Glon is a drug that acts very quickly and very violently; the throbbing (head) is not a mere sensation, it is an actual fact. It really seems that the blood vessels would burst, so violent is the action of the drug. The blood seems to surge in one great current up the spine and into the head. The external jugulars look like tortuous cords, the carotids throb violently and are hard, tense and unyielding to pressure. The face is deep red. This throbbing is either associated with dull, distressing aching,or with sharp, violent pains." "Sunstroke also we find Glon. to be our best remedy for the effects of heat,whether the trouble arises from the direct rays of the sun, from hot weather, or from working in the intense heat of a furnace, as in the case of foundrymen and machinists. these effects are not confined to the head, but involve the whole body,and we note oppression of breathing,with palpitation of the heart and nausea and vomiting the nausea not gastric, but cerebral a horrible, sunken feeling in the epigastrium and often, too,diarrhoea. Eyes too large and protrude as though bursting out of the head eye diseases from exposure to very bright light blood vessels of retina distended, or, in extreme cases, apoplexy of the retina. Admirable remedy for puerperal convulsions: full, heard pulse, and albuminuria." "Well-known streets seem strange to the patient (Petroleum). Suppose a person, subject to apoplectic congestions, is suddenly seized in the streets with one of these,and does not know where he is,then Glonoine is the remedy for him." "Bad effects of fear (Opium). Horrible apprehension,and sometimes the fear being poisoned." "Then, trauma. An excellent remedy for pains and other abnormal sensations,following late after local injuries: the part pains, or feels sore; or an old scar breaks out again." He, also,contracts Bell. and Glon."because they meet in the congestions and inflammations of the brain with children and old persons. The divide the honours here." BELL. GLON. Cri encephalique. Less marked. Worse bending head backwards. Better bending head backwards Head feels enormously large. Better for uncovering head. Better from covering head. Better open air. We will end by extracting some of KENT'S most graphic little flashes; even where there is repetition,that merely serves to emphasize and drive the facts in. "Surging of blood to heart and head. As if all the blood in the body were rushing round the heard: a surging in head; a warm, glowing sensation in head; or in tense glowing from stomach or chest up to head, at times with loss of consciousness. Wave like sensations,as if skull were lifted and lowered; expanded and contacted. Intense pain, therewith, as if head would burst. Great throbbing: : beating of hammers; every pulsation painful. Even fingers and toes pulsate." "Head is relieved in open air: worse in warmth, often relieved by cold. Worse lying, Worse head low. Extremities cold, pale and perspiring, head hot, face flushed and purple or bright red. Mouth dry; eyelids dry, stick to eyeballs., All degrees of confusion to unconsciousness.": "Sunstroke sudden congestions of head. Cold feels good to head; heat feels good to extremities. When lower limbs are covered with clothing in a cool room,and windows open, convulsions are relieved,and patient breathes more easily." "In apoplexy,such medicines as Opium and Glonoine relieve the blood pressure when the symptoms agree. They equalize the circulation,and the patient may not die." "If sitting up, you will often see a Glonoine patient with both hands pressing upon the head with all the power possible until the arms are perfectly exhausted. Wants it bandaged, or a tight cap. Worse from wine, and worse from lying down. You will be astonished to know how long a Glonoine patient will sit without moving a muscle, because motion is so painful. Whole crown of head feels as if covered by a hot iron,as if an oven were close by.".
Introduction:
GLONOINE-Nitro-glycerine-that highly explosive liquid , which, admixed with some pours earth forms the "deadly dynamite to the shaking of earth and the blasting of rocks ,lives up to its reputation, even when potentized and used in medicine; retaining its alarming characters: its suddenness, its bursting sensations and pains,its upward-surging which threaten to lift and shatter the cranium. Chemistry is fascinating, of only for its psychology, if one may (mis) use the term. Of two deadly elements, in combination,she may form something quite harmless,m even essential to life: whereas from such mild and kindly creatures as the glycerine of the toilet table so inert that it never even "goes bad", and nitrogen, that colourless, tasteless, odourless gas, which, four- parts to one in mixture with the life-supporter, oxygen, modifies the properties of the latter in such sort that, instead of burning us out rapidly, we just get, with every breath, that happy admixture that supports life without hastening its destruction. That nitrogen and glycerine should combine to produce such a wildly intemperate blasting agent is incalculable- absolutely unforeseen till "discovered". But, as a great chemist once said, "no one could tell, a priori, how even a lump of sugar would behave when dropped into a cup of tea". Science is the plodding daughter of Experiment: and, as such, Homoeopathy is scientific. Dr. HUGHES (Pharmacodynamics) points out that, though Old School uses Glonoine, having even adopted that name for it, yet medicine owes its introduction to Constantine Hearing, Hahnemann's great disciple. But we notice that, as always, when using those violent medicinal substances, so often the most splendidly curative agents of Homoeopathy, Old School has, perforce, to follow into the fantastic region of infinitesimals. "Nitro-glycerin was discovered by Sobrero in 1847, but none could be obtained for physiological experiment until Morris Davis, a Philadelphia chemist, in the same year, after long and laborious trials, under direction of Hering, succeeded to produce the substance in sufficient quantity for proving. It was extensively proven here and abroad (see Allen's "Encyclopedia") and the symptoms have received abundant clinical verification."-- HERING'S "Guiding Symptoms" A quaint little verification of the care and exactness with which the provings of homoeopathic drugs have been observed and recorded comes to hand, most opportunity, even as we write. A certain physician,busy with rather urgent mental work,and worried by a sensation of fullness at the back of head and neck, -a miserable, incapacitating fullness-took a dose of Glonoine--a drug that, as we know, produces such fullness,and there. It was Glonoine 3, merely a couple of pilules, of the only preparation available, probably inert, discovered among a number of homoeopathic medicines that had belonged to some on long since dead-(certainly 25 to 30 years) Well, the headache soon went (post or proper hoc?)-but a couple of days later,while busy with out-patient work, the doctor became suddenly conscious of an unpleasant numbness of the left had, never felt before,and rather disconcerting. Presently this disappeared,but only to be succeeded by numbness of the lower lip, -the exact sensation felt when cocaine has been injected for tooth extraction,. this also went: but only to return again and again and yet again first to left hand and then to lower lip: nowhere else: always absolutely limited. Before night these rather alarming sensations sent him to Kent's Repertory to find the remedy-should it be needed. And there he discovered,under "numbness, lower lip{, drugs only "(Calc),and Glon." Then he turned to "Numbness of left hand", to find several remedies: Glon. among them! The sensation was satisfactorily accounted for: and was the more interesting because Glon. is not down as producing numbness of right hand, or of upper lip.
BLACK LETTER SYMPTOMS
Well-known streets seem strange: way home too long. Disinclined to speak; would hardly answer. A distinct feeling of pulse in HEAD Throbbing in front of head. Immediately a sensation as if head were too large. Head felt enormously large. Pressure and throbbing in temples. Pressure and pain from within out in both temples. Fullness in head,and throbbing without pain. Head very full: pulse full;l and quick. As if the blood were mounting to head. As if he were hanging with head downwards,and as if there were a great rush of blood into head in consequence. As if skull were too small; and brain attempting to burst it. Afraid to shake his head lest it drop top pieces. Holds head with both hands; presses sinciput. Shocks in brain, synchronous with every pulsation of arteries. Undulating sensation in head. Throbbing in head: in temples: in temporal arteries which were raised and felt like whipcords. Sensation of fullness, vertex and forehead. Shaking the head increases the headache. Headache on damp,rainy days; after taking cold; after much sitting, and mental exertion. Red injected hot EYES during headache, with wild expression. Throbbing pain in all the TEETH. Throbbing in while BODY. Intense congestion of brain induced in plethoric constitutions by sudden SUPPRESSION OF MENSES, or appearing instead of menses. Headaches occurring after profuse uterine haemorrhage. Rush of blood to head in pregnant women, with pale fact and loss of consciousness. Violent palpitation of HEART, with throbbing carotids,pulsating headache in forehead and between temples. Blood seems to rush to heart and mount rapidly into head. Epileptic CONVULSIONS,with congestion to head and heart. Bad effects from being exposed immediately to SUN'S rays. (In fever) flushes of heat: weaves of heat upwards.
ITALIC, OR QUEER SYMPTOMS
Recognized no one. Raved; screamed wishes to rush from house. Jumped out of bed,but legs gave way. Fears: throat swollen;chest as if screwed together; of approaching death; of having been poisoned. Bad effects of fear,fright,mechanical contusions and their late consequences. Could not allow head to be level with body. Confusion of ideas: could not tell where he was. Loss of location: (a cured case) began ten years ago; loses himself in streets he was travelled in for years. All right in regard to everything else. In familiar street everything strange. Had to look about him every few minutes to convince himself he was in. he right street. Houses not in their right places, on the route he had traversed at least four times a day for four years. Convulsions,falls down from thing at mouth, after alternations of palpitation of heart and congestions to the head. Congestion to head,causes sensation of coldness every time. Tight and khaki feeling throat,k like strangulation. Skull too small. as if brain attempting to burst skull. As if head and neck laced ion: clothing too tight. Pain in wens on scalp. as of a thimble pressed firmly on them. Every motion,side to side,. increased the pain (in head), but motions backward and forward did not. Headache: ceases in sleep: better in open air:;lessened by drinking coffee, after a raw hours: tea lessens it better. Feels as if ice-cold sweat were on forehead,.which is not there. Rays of sun on head were not to be borne, and head would not allow hat to touch it. Frightful headache: runs about room with head pressed between hands. As if head would burst: knocks it against wall. Hyperaemia of brain caused by excessive cold or heat. Bad consequences of cutting hair. SUNSTROKE. Said her eyes were falling out: felt as if someone were pulling them from within outwards. Letters seem smaller: flashes of lightning,sparks, mist or black spots,whirling and confused vision. Wild, staring look : protrusion of eyes. Supra-orbital neuralgia,from 6 a.m. to 11 or 12. Cold sweat on face during congestion to head. Lower lip feels swollen. Numbness lower lip. Chin feel elongated to knee's: obliged to put hand to chin repeatedly to be sure this was not the case. (Prover had injured chin by a fall twenty years before.) Tongue numb as if burnt; prickling, stinging.' Constriction in throat as if throttled. Wine aggravates all symptoms: alcoholic stimulants cause delirium, congestion,stupor. Seasickness. Faint, warm sickening sensation in chest and stomach, like threatening seasickness Giddiness. Disturbances in intercranial circulation at menopause. Flushes, etc., during climacteric. Violent palpitation: feeling she would die: Numbness whole of the left arm. Pressure at heart as if it were being contracted. Alternate congestion to heart and to head. "As an intercurrent in angina pectoris, to prevent organism from, getting accustomed to unlicensed of Aur. mur." Hot sensation down back; burning between scapulae. Old contusions and jars (to head and spine). Knees give way in headache. Unsteady gait. Knees and thighs knock together during headache. Convulsions, with clenching and jerking upwards of fists and legs. During spasms spreads fingers and toes apart. Convulsions,with especially left fingers spread apart. Cannot protrude tongue in a strains line. Restless sleeps: wakes with fear of apoplexy. Congestions; blood tends upwards: vessels pulsate; veins, jugular temporal, enlarged. Rapid deviations in distribution of blood. Useful as a substitute for bleeding. Bad effects from mental excitement, fright fear, mechanical contusions and their later consequences,from having hair cut,and from exposure to rays of sun. Antidoted by ACON., Camph., Coffea, Nux. Compare AMYL NITR., Bell., Ferr., Gels., Natrum Carb., Potassium. nitr., Sod. nitr., Stram. As seem from above, the action of Glonoine so local., so sudden,so definite,so alarming and torturing,and therefore so remedial is, once grasped,impossible to forget. In fact, it seems hardly worth writing about ! However we will run through what some of or great prescribers and writers have to say about it. This one emphasizes one point coinciding with his experience,that one another; and so one learns. HUGHES writes: "The name Glonoine was formed by its introducer into medical practice,,Dr. C.Hering, out of the chemical formula (GlO NO5) denoting its composition. Dr. Hering proved it on himself and others in 1948. Hughes says, "The action of Glonoine lies a within a very small compass. If any one will touch his tongue with a 5 per cent. solution,he will pretty certainly find in a few minutes that his pulse has increased by twenty,forty or even sixty beaten. He may feel throbbing all over his body, but will almost always experience it in his head which will go on beating until a pretty violent bursting headache has developed itself. With this, there will be probably some giddiness, a sense of fullness on the head and at the heart,.and ones of constriction about the throat. All this reminds used of Amyl nitrite but the effects of the two drugs are not identical. Amyl causes a general flushing without marked sense of throbbing nor is the pulse much affected by it. It seems to have been demonstrated that Amyl produces its dilating effects on the arteries by directly paralysing their muscular coats while Glonoine affects the nervous centres of the circulation,and is limited to this sphere." Then he distinguishes between the action of Glon. and Belladonna. "With Bell., the circulation within the cranium is excited because the brain is irritated: with Glon., the brain is irritated because the circulation is excited. It would be indicated in such hyperaemia as can be produced by excessive heat or cold, by strong emotions,by mechanical jarring,by suppression of the menses or other haemorrhage and excretions." He evidences not only sunstroke, but the striking benefit he has obtained from the drug in the distressing after-effects of sunstroke. He says, "perhaps the greatest boon which Dr. Hering has conferred upon patients in introducing Glon, to medicine is the relief it gives to menstrual disturbances of the cerebral circulation as the intense congestion of brain induced in plethoric constitutions by sudden suppression of the menses. Glonoine is an exquisite similimum here: for in one of Dr. Dudgeon's provers,who took it while an catamenia were present, these immediately ceased,and the headache went on increasing in violence till night. It does not, like Lachesis or Amyl nitrite, act on the flushings of the climacteric; but is most valuable when these are localized in the head. He says, "it was the statement of its discover, Soberer, that even a very small quantity placed on the tongue causes a violent headache of several hours' duration', which led Dr., Hering to investigate its action." The kind of headache--fullness, tension, throbbing, bursting-- these are the phrases used by the provers to describe it. It acts as rapidly in disease as in health. He discusses its stroking power to relieving paroxysms of neuralgia, even in some cases, permanently curing. GUERNSEY epitomizes Glonoine,.and its uses. "Troubles from heat of the head in type-setters in men who work under a gas-light steadily, so that heat falls on the head: bad results from sunstroke; can't bear any heat about the head; can't walk in the sun, must walk in the shade or carry an umbrella; can't bear heat from a stove; great vertigo from assuming an upright posture from rising up in bed, rising from a seat. Heat in head;throbbing headache." Patient feels lost, or strange even in unfamiliar street or surroundings. Things look strange and unfamiliar. NASH. One of our great head ,medicines. He says he used to carry Glon I in his case, for those inclined to sneer at the young doctor and his sweet medicine. He seldom failed to convince, in five to ten minutes, that there was power here; for a drop on the tongue produced the characteristic throbbing headache. No one ever asked for more proof of the power of Homoeopathic medicine. (One members a young woman doctor at the"New":, as the Elizabeth Garret Anderson Hospital was then called, who described the terrible headache from touching her tongue with some preparation of nitro-glycerine). The pains of Belladonna are sudden in onset, and suddenly gone: those of Glonoine are even more so. Nash says that "Glonoine is better adapted to the first, congestive stage of inflammatory diseases of the brain: Belladonna goes farther, and may still be the remedy after the inflammatory stage is fully initiated." Neither can stand the least jar. But pain "waves" upsurging, are absolutely characteristic of Glon. FARRINGTON emphasizes that the keynote to the whole symptomatology of the drug is expressed in this one sentence: "a tendency to sudden and violent irregularity of the circulation." With that, he says,we can easily work out the other symptoms. "Glon is a drug that acts very quickly and very violently; the throbbing (head) is not a mere sensation, it is an actual fact. It really seems that the blood vessels would burst, so violent is the action of the drug. The blood seems to surge in one great current up the spine and into the head. The external jugulars look like tortuous cords, the carotids throb violently and are hard, tense and unyielding to pressure. The face is deep red. This throbbing is either associated with dull, distressing aching,or with sharp, violent pains." "Sunstroke also we find Glon. to be our best remedy for the effects of heat,whether the trouble arises from the direct rays of the sun, from hot weather, or from working in the intense heat of a furnace, as in the case of foundrymen and machinists. these effects are not confined to the head, but involve the whole body,and we note oppression of breathing,with palpitation of the heart and nausea and vomiting the nausea not gastric, but cerebral a horrible, sunken feeling in the epigastrium and often, too,diarrhoea. Eyes too large and protrude as though bursting out of the head eye diseases from exposure to very bright light blood vessels of retina distended, or, in extreme cases, apoplexy of the retina. Admirable remedy for puerperal convulsions: full, heard pulse, and albuminuria." "Well-known streets seem strange to the patient (Petroleum). Suppose a person, subject to apoplectic congestions, is suddenly seized in the streets with one of these,and does not know where he is,then Glonoine is the remedy for him." "Bad effects of fear (Opium). Horrible apprehension,and sometimes the fear being poisoned." "Then, trauma. An excellent remedy for pains and other abnormal sensations,following late after local injuries: the part pains, or feels sore; or an old scar breaks out again." He, also,contracts Bell. and Glon."because they meet in the congestions and inflammations of the brain with children and old persons. The divide the honours here." BELL. GLON. Cri encephalique. Less marked. Worse bending head backwards. Better bending head backwards Head feels enormously large. Better for uncovering head. Better from covering head. Better open air. We will end by extracting some of KENT'S most graphic little flashes; even where there is repetition,that merely serves to emphasize and drive the facts in. "Surging of blood to heart and head. As if all the blood in the body were rushing round the heard: a surging in head; a warm, glowing sensation in head; or in tense glowing from stomach or chest up to head, at times with loss of consciousness. Wave like sensations,as if skull were lifted and lowered; expanded and contacted. Intense pain, therewith, as if head would burst. Great throbbing: : beating of hammers; every pulsation painful. Even fingers and toes pulsate." "Head is relieved in open air: worse in warmth, often relieved by cold. Worse lying, Worse head low. Extremities cold, pale and perspiring, head hot, face flushed and purple or bright red. Mouth dry; eyelids dry, stick to eyeballs., All degrees of confusion to unconsciousness.": "Sunstroke sudden congestions of head. Cold feels good to head; heat feels good to extremities. When lower limbs are covered with clothing in a cool room,and windows open, convulsions are relieved,and patient breathes more easily." "In apoplexy,such medicines as Opium and Glonoine relieve the blood pressure when the symptoms agree. They equalize the circulation,and the patient may not die." "If sitting up, you will often see a Glonoine patient with both hands pressing upon the head with all the power possible until the arms are perfectly exhausted. Wants it bandaged, or a tight cap. Worse from wine, and worse from lying down. You will be astonished to know how long a Glonoine patient will sit without moving a muscle, because motion is so painful. Whole crown of head feels as if covered by a hot iron,as if an oven were close by.".
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